The bout was announced by UFC CEO, Dana White.
Sean Brady had his last fight last December, finishing Kelvin Gastelum with a third-round kimura. In doing so, the 31-year-old American put his career back on track after suffering his first professional defeat since October 2022, losing by second-round technical knockout to Belal Muhammad.
Vicente Luque, 32, also returns to the octagon after winning a unanimous decision over Rafael Dos Anjos. The 32-year-old Brazilian had previously suffered two straight losses, losing by unanimous decision to Belal Muhammad and losing by knockout to Jeff Neal.
Sean Brady and Vicente Luque are currently ranked seventh and ninth in the UFC welterweight division rankings, respectively.